Sicca syndrome
  • Keratoconjunctivitis sicca, dryness of mucous membranes, telangiectasias or purpuric spots on the face, and bilateral parotid enlargement; seen in menopausal women and often associated with rheumatoid arthritis, Raynaud phenomenon, and dental caries; there are changes in the lacrimal and salivary glands resembling those of Mikulicz disease. Syn: Gougerot-Sjögren disease, Sjögren disease.
Dry eyes
Dry mouth
Swollen parotid glands +/- (Mikulicz syndrome)
graphic
Fig. 5-31 Sjögren syndrome. A, Enlargement of the salivary gland. B, The histologic view shows intense lymphocytic and plasma cell infiltration with ductal epithelial hyperplasia. (A, Courtesy of Dr. Richard Sontheimer, Department of Dermatology, University of Texas Southwestern Medical School, Dallas; B, courtesy of Dr. Dennis Burns, Department of Pathology, University of Texas Southwestern Medical School, Dallas.)
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