Primary biliary cirrhosis (anti-mitochondrial antibodies)
  • A condition occurring mainly in middle-aged women, characterized by obstructive jaundice with hyperlipemia, pruritis, and hyperpigmentation of the skin; no obstruction of large bile ducts or proliferation of small bile ducts is found; the liver shows cirrhosis with marked portal infiltration by lymphocytes and plasma cells, and frequently by epithelioid cell granulomas; serum antimitochondrial antibodies are present in 85–90% of patients. Syn: Hanot cirrhosis.
Top