Fig. 5-14
Immune complex deposition in the glomerulus. A, Membranous
glomerulonephritis. Electron micrograph showing electron-dense deposits (arrow) along
the epithelial side of the basement membrane (B). B, Immunofluorescence micrograph
stained with fluorescent anti-IgG from a patient with diffuse proliferative lupus nephritis.
One complete glomerulus and part of another one are seen. Note the mesangial and
capillary wall deposits of IgG. CL, capillary lumen; End, endothelium; Ep, epithelium. (B,
Courtesy of Dr. Helmut Rennke, Department of Pathology, Brigham and Women’s
Hospital, Boston.)