7.2.2 Mechanisms
  • Loss of tolerance for self-antigens
  • Immune response against self (auto) antigens
  • Release of intracellular antigens
  • Molecular mimicry
  • structural similarity between self-antigens and microbial antigens
  • Polyclonal lymphocyte activation
  • Antibody or dell-mediated damage
  • Other
  • Genetic
  • Environment
  • Hormones
  • Drugs
  • Infection
  • UV radiation
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